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The Stout Lab is looking for a highly motivated postdoctoral research fellow to join the multidisciplinary laboratory within the Aging & Metabolism (A&M) Research Program at OMRF. The fellow will investigate the basic mechanisms that underlie gonadal aging and/or hypothalamic–pituitary–gonadal axis dysfunction with advancing age. The successful candidate will employ a wide range of techniques including the generation of novel mouse models, isotopic labeling, single-cell transcriptomics, spatial transcriptomics, histology & pathological assessments, and a variety of other cellular & molecular biology techniques.
The candidate will present their data regularly in laboratory meetings, local seminars and symposiums, and will have opportunities to present their work at national conferences. A requirement of the position is that the candidate must demonstrate ethical behavior at all times, a high-level of scientific rigor, and must be detail-oriented and able to work independently and as part of a team.
Category Scientific
ID 2023-1580
Department Aging & Metabolism - Stout
Classification On-going
Job Locations US-OK-Oklahoma City
A postdoctoral research position is available in Dr. Jasim Ahamed’s laboratory to study the role of TGF-beta in organ fibrosis and cardiovascular disease (Antioxid Redox Signal. 2021 (PMID: 34619980); AIDS. 2020 Jun 1;34(7):989-1000 (PMID¨32167970); Blood Adv. 2019 Mar 12;3(5):777-788. (PMID: 30846427); Meyer et al. Blood 2012, 119:1064. (PMID:22134166). We are seeking individuals with experience in biochemistry, molecular biology, in vivo mouse models for cardiovascular disease, and ultrasound imaging techniques.
Category Scientific
ID 2023-1575
Department Cardiovascular Biology - Ahamed
Classification On-going
Job Locations US-OK-Oklahoma City
The Montgomery Lab is a translational laboratory focused on understanding the mechanisms of complex diseases known to have genetic underpinnings and immune dysregulation. We have a particular interest in sarcoidosis, a granulomatous disorder that disproportionately affects women and people of African ancestry. We focus to better understand the pathogenesis of disease through immunological characterization and genomic profiling. We have large, complex datasets partnered with detailed clinical data to improve the lives of patients with of immune-mediated diseases. The successful candidate will be part of a dynamic team with synergistic skills and experiences and will be given the opportunity to develop projects that complement the overall directions of the group. The team utilizes high throughput assays, deep phenotyping, single cell genomic, proteomic, and computational and bioinformatics analyses. We also have access to high performance computational resources both in-house and through cloud-based resources.
Trainees have the opportunity to participate in large, NIH-funded consortia like TOPMed. This position also allows for cross-training in the data sciences via the OMRF Center for Biomedical Data Sciences for which Dr. Montgomery is the Director. This is a mentored position for postdoctoral training. Individuals at this level plan, design and conduct research experiments; manage research projects; prepare reports and papers for publication, presentation and future research; contribute to grant writing and are encouraged to write applications for fellowships; learn the complexities of research lab management and participate in various lab activities. Benchmark Expectations - Conduct scientific research - Manage research projects - Present scientific information both formally and informally - Prepare papers for publication - Contribute to grant writing - Perform lab responsibilities as assigned - Work collaboratively and collegially as part of the team while developing skills needed as an independent scientist. Knowledge, Skills, and Abilities Knowledge of the principles and practices of scientific theory and research; demonstrates skill in formulating and testing hypotheses; demonstrates ability to conduct scientific research analysis and summarize data and results; writes technical, scientific papers; writes grants and communicates effectively both orally and in writing; mentor students; provides analytic support and input to other projects in the group and guides/directs the work of less senior scientists.
Category Scientific
ID 2023-1565
Department Genes & Human Disease - Montgomery
Classification On-going
Job Locations US-OK-Oklahoma City
The Bodine Lab is seeking a Post-doctoral Fellow. Incumbents at this level will be mentonerd and will plan, design and conduct research experiments; manage research projects; prepare reports and papers for publication, presentation and future research; contribute to grant writing and are encouraged to write applications for fellowships. Learn the complexities of research lab management and participate in various lab management responsibilities.
Category Scientific
ID 2023-1564
Department Aging & Metabolism (A&M)
Classification On-going
Job Locations US-OK-Oklahoma City
We are looking for a highly motivated postdoctoral research fellow to join the multidisciplinary Stout Laboratory within the Aging & Metabolism (A&M) Research Program at OMRF. The fellow will investigate how sex hormones and their receptors modulate hypothalamic neurocircuitry and the sex-specific regulation of systemic metabolism during the aging process. The successful candidate will employ a wide range of techniques including stereotaxic injection of AAVs into the brain, chemogenetic approaches (DREADD), brain imaging, single-cell transcriptomics, in vivo metabolic assessments, and a variety of cellular & molecular biology techniques. The candidate will present their data regularly in laboratory meetings, local seminars and symposiums, and will have opportunities to present their work at national conferences. A requirement of the position is that the candidate must demonstrate ethical behavior at all times, a high level of scientific rigor, and must be detail oriented and able to work independently and as part of a team. The Stout Laboratory and A&M Research Program welcome applicants from diverse backgrounds that thrive in a highly collaborative and supportive environment.
We are strongly committed to providing individualized mentoring and assistance with career advancement through the implementation of a postdoctoral mentoring committee. The A&M Research Program, which currently consists of 13 highly collaborative investigators, provides an exceptional training environment in aging biology (Geroscience). The A&M Research Program also has a strong collaborative history with faculty from the Oklahoma Center for Geroscience and Health Brain Aging at OUHSC which has resulted in a Geroscience Training Grant (T32 AG052363) that supports graduate students and postdoctoral fellows at OMRF and OUHSC. The collaborative program also houses the Oklahoma Nathan Shock Center of Excellence in Basic Biology of Aging (P30 AG050911), which provides pilot funding for junior investigators. OMRF also offers an annual grant writing course (F-troop) for graduate students and postdoctoral fellows that plan to prepare grant applications (F- or K-awards) for the NIH. The OMRF Postdoctoral Association offers additional training opportunities related to grant writing, presentation skills, and career development. The vibrant and highly collaborative environment within OMRF has resulted in the foundation being named the top large employer in the state of Oklahoma three times in the last five years.
Category Scientific
ID 2023-1559
Department Aging & Metabolism - Stout
Classification On-going
Job Locations US-OK-Oklahoma City
The Lee laboratory at the Cardiovascular Biology Research Program (CVB) of OMRF is seeking Postdoctoral Fellows to lead research projects. Our NIH-funded research program (https://leelab.omrf.org/) investigates mechanisms linking mitochondrial and NAD+ metabolism to pathogenesis of cardiometabolic diseases. Fellows will have access to resources and equipment for cardiac physiology and electrophysiology, metabolism, cardiomyocyte and mitochondrial function, proteomics, metabolomics, informatics and spatial transcriptomics from the Lee lab, CVB, CMRO-CoBRE (https://cellularmetabolism-cobre.omrf.org/), OMRF core facilities (https://omrf.org/research-faculty/core-facilities/) and collaborations. Candidates must be self-motivated, proactive and enthusiastic about their research career development.
The Principal Investigator (PI) and the postdoctoral mentoring committee will be committed to prepare fellows for an independent research career. Candidates are expected to work independently and contribute intellectually to facilitate a stimulating environment within the research group and among research programs at OMRF. OMRF’s postdoctoral fellow association (https://omrf.org/about-omrf/education-outreach/postdoctoral-programs/postdoc-association/) seeks to enhance the training experience by providing scientific, social interaction opportunities and funds to support attendance at scientific meetings or workshops. Successful candidates will have a recent doctoral degree (within 0-3 years or expect to receive the degree within a year) in cardiovascular physiology, biochemistry or related biomedical disciplines. First-authored publication(s) from the graduate work is expected. Prior research experience and publication(s) investigating cardiometabolic diseases in mouse model are required. Experience in echocardiography, electrophysiology and surgical techniques for heart disease is a plus.
Category Scientific
ID 2023-1554
Classification On-going
The Yoon Lab is looking for a highly motivated, creative, and responsible scientists who will play a key role in achieving the mission of the lab. We aim to discover cellular and molecular mechanisms of Mendelian mitochondrial diseases. To do this, we implement an experimental pipeline that leverages the combined power of clinical data, genomics analysis, and studies using Drosophila models and patient-derived stem cell models. We have discovered 5 new Mendelian mitochondrial diseases including the Harel-Yoon syndrome that bears my name. We have established disease models in Drosophila and human iPS cells. Hence, the motivated postdoctoral researchers are expected to discover new findings and publish high-impact papers. Researchers with strong interest in neurological and mitochondrial diseases are welcome to apply. Expertise in any of the following areas is highly valued though not required: - Drosophila genetics - Metabolism/mitochondrial biology - Neurodegeneration & Neurodevelopmental diseases - Developmental biology - iPSCs/cerebral organoids
Category Scientific
ID 2022-1442
Classification On-going
The Finn Lab at OMRF is looking for excellent candidates for a position at the level of postdoctoral research fellow. We study how variability in genome organization can give rise to cellular phenotypes. You will be trained in techniques specific to the lab. You will bring your own expertise. Together, we’ll develop an exciting, independent research project that you will oversee and manage. As the work develops, there will be opportunities for grant-writing, mentorship of students, publication, and formal and informal presentations. The eventual goal is to help you build the independence you need to advance your career. Benchmark Accountabilities: • Independently conducts scientific research • Oversees and/or manages a research project • Mentors more junior lab members • Shares in regular lab maintenance tasks • Assists with grant writing and writing papers for publication • Apply for training grants and other funding if eligible with assistance and guidance • Presents scientific information both formally and informally Knowledge, Skills, and Abilities: • Knowledge of the principles and practices of scientific theory and research • Skill in formulating and testing hypotheses • Verbal and written communication skills • Ability to design and conduct scientific research experiments • Ability to analyze and summarize data and results • Ability to write scientific papers and grants • Ability to mentor students and guide the work of less senior scientists
Category Scientific
ID 2022-1502
Department Cell Cycle & Cancer Biology - Finn
The Rankin Lab is seeking a Post-doctoral Fellow to study chromosome assembly and dynamics, how these events are controlled, and how corruption of these processes contributes to disease. Our lab forms part of the Program in Cell Cycle and Cancer Biology, which offers an excellent training environment in a state-of-the-art facility. We use a variety of experimental models, including cultured cells, biochemistry, extracts from frog eggs, and advanced microscopy to address problems of chromosome structure, replication, and inheritance. Experience directly related to this field is not necessary, but basic molecular biology skills are preferred. Applicants should demonstrate enthusiasm for the topic, willingness to learn, and the ability to work independently to develop their project(s), analyze experiments, and prepare manuscripts. Successful candidates will have good written and verbal communication skills and be willing to engage fully in lab and departmental activities. During their tenure in the Rankin lab, fellows will receive significant career development support. They can also expect to attend training courses as well as scientific conferences, where they can present their work and establish their presence in the research community.
Category Scientific
ID 2023-1545
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