1. Postdoctoral Associate | Kumar Lab
Location: Bar Harbor, Maine
Job Number: 7122305 (Ref #: JR001138)
Posting Date: Jan 27, 2023
Application Deadline: Open Until Filled
Job Description
Job Posting Template
Postdoctoral Associate – Molecular Genetics of Addiction – Kumar lab
A postdoctoral position is available in the laboratory of Dr. Vivek Kumar at The Jackson Laboratory (JAX) in Bar Harbor, Maine. We seek a postdoctoral fellow to study the neural circuitry underlying reward and motivation in the context of addiction in the mammalian brain. The position is ideally suited for an individual with a strong background in animal behavior who is also interested in learning mouse molecular genetics and genomics to address important neurobiological questions. Dr. Kumar and his colleagues at JAX have significant expertise in the genetics of complex traits, and ample opportunities will be provided for independent training in cutting edge genomics, including genome editing and single cell genomics. For more information, please visit www.kumarlab.org
We seek motivated candidates, with Ph.D. degree or nearing completion of Ph.D., who will be eager to take advantage of the unique opportunities available at JAX to advance their careers by combining existing neuroscience expertise with unparalleled genetics and genomics training. Emphasis is placed on training the next generation of scientific leaders through the JAX Whole Scientist Program. Exceptional candidates can show early independence through the JAX Scholars Program. JAX has a vibrant and interactive research community with unparalleled mouse resources and state of the art facilities for mouse neurobehavior, computational science, mass spectrometry, imaging science, and genome technologies. JAX is located on Mount Desert Island on the coast of Maine and is adjacent to Acadia National Park, renowned for its scenic beauty and many venues for outdoor recreation.
Required Skills:
We value the ability to plan, execute and analyze an independent research project as well as exceptional verbal, written communication skills, adaptability, and lifelong learning.
Qualifications:M.D. or Ph.D. in biological or related life sciences is required.
Background in rodent behavior and addiction phenotyping, with interests in learning genetics and genomics.
Exceptional communication skills;
Self-motivated;
Experience working with rodent models
To apply, please submit a current CV, a cover letter outlining research interests, and names and contact information for three references.
About JAX:
The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,400 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center in Augusta, Maine, a genomic medicine institute in Farmington, Connecticut, and facilities in Ellsworth, Maine, Sacramento, California, and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!
EEO Statement:
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
2. Computational Postdoctoral Associate | Varn Lab
Location: Farmington, Connecticut
Job Number: 7122720 (Ref #: JR003029)
Posting Date: Feb 1, 2023
Application Deadline: Open Until Filled
Job Description
Postdoctoral Associate | Computational Cancer Biology
Varn Lab
Farmington, CT
The Varn Lab at The Jackson Laboratory for Genomic Medicine (JAX) is seeking a postdoctoral associate to study the role of tumor-microenvironment interactions in shaping the evolutionary trajectory of diffuse glioma, the most common malignant brain tumor in adults. The Varn Lab integrates genomic and molecular pathology approaches to study how the neurons, glial cells, and immune cells of the brain tumor microenvironment influence the transcriptional output of malignant glioma cells. Projects in the lab grow out of previous work done in collaboration with the Glioma Longitudinal Analysis (GLASS) Consortium (see Varn et al, Cell, 2022). We are seeking applicants that have interest in integrating data from cutting-edge genomic and microscopy techniques to investigate the role of the microenvironment in cancer evolution. For additional information, visit the Varn Lab’s webpage at jax.org.
The ideal candidate for this role will be motivated, curious, and have an established track record in computational biology, genomics, or a related quantitative area. Previous experience in single-cell analysis is a plus, but not required. Individuals in this position will have access to state-of-the-art scientific resources at JAX as well as primary tissue samples through collaborative agreements between the Varn Lab and medical institutions. Scientific research will be conducted in a laboratory that is heavily invested in the mentoring, career development, and success of trainees. This mentoring will be supplemented with institutional resources that include year-round workshops hosted by JAX, scientific writing services, and intramural funding opportunities. Overall, individuals will be well-supported to grow their careers while conducting exciting research that blends the fields of cell biology, microscopy, and computational biology.
Key Responsibilities Apply and develop computational methods to analyze cell-cell interactions using bulk, single-cell, and spatial datasets
Manage and organize human tissue samples
Employ critical and creative thinking skills to solve scientific problems
Synthesize scientific literature into new project ideas
Collaborate with other labs at JAX to integrate new techniques into the laboratory
Write manuscripts and, in the long-term, apply for independent funding
Present results at lab meetings, institutional symposia, and national conferences
Qualifications PhD in Genetics, Computational Biology, or a related field
At least one first author publication in a peer-reviewed journal
Experience in R, Python, or a related language
Strong managerial and organizational skills
Ability to drive projects forward and take initiative in solving problems
A personal growth mindset and receptiveness to constructive feedback
A desire to work with others, both collaboratively and as a mentor
Excellent written and oral communication skills to disseminate results and methods to the group
Interested applicants should send their CV (including three references) and a cover letter to Frederick.Varn@jax.org.
About JAX:
The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,400 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center in Augusta, Maine, a genomic medicine institute in Farmington, Connecticut, and facilities in Ellsworth, Maine, Sacramento, California, and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!
EEO Statement:
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
3. Postdoctoral Associate | Wei Lab
Location: Farmington, Connecticut
Job Number: 7125236 (Ref #: JR001993)
Posting Date: Feb 16, 2023
Application Deadline: Open Until Filled
Job Description
Postdoctoral Associate
Dr. Chia-Lin Wei, Principal Investigator
The 3D Chromatin Genomics Lab at JAX-GM is seeking to appoint a postdoctoral associate to participate in research directed toward elucidating the structures and dynamics of complex genomes. For more on the Wei Lab’s research and goals, visit: https://www.jax.org/research-and-faculty/faculty/chia-lin-wei
Postdoctoral Positions in Three-dimensional (3D) Chromatin Genomics
Chromatin interactions and its 3D structure play a major role in regulating gene expression by bringing together regulatory elements that are distal on the linear genome in close physical proximity with each other. Our Lab have pioneered genomic technologies for genome-wide profiling chromatin interactions. We are seeking enthusiastic, highly skilled computational and experimental post-docs to generate and analyze human chromatin interaction datasets in integration with other genomics and genetics datasets.
We are seeking postdoctoral researchers to develop computational and genomic approaches for understanding 3D genome biology under the light of diverse genomic and genetic information. We are seeking self-motivated, independent individuals who are interested in building their own career paths; however, postdoctoral fellows are expected to coordinate with and report to the PI responsible for the research area(s) addressed by their project. The fellows will develop research projects in one or more areas of focus:
• 3D genome mapping and imaging technologies
• Application of nano-engineering toward genomic methodologies
• Computational modeling of 3D genome architectures
• Building regulatory networks at multiple layers including gene expression, epigenetic, and chromatin data
• Integrating regulatory interactions with genetic data
• Mining and aligning chromatin interaction datasets in diverse human cell types
• Functional perturbation of topological elements
Our Postdoctoral Associates enjoy distinct advantages, including:
• Advanced research in 3D epigenome technology and Biology.
• A uniquely collaborative environment that fosters interdisciplinary “team science” without departmental barriers
• Unparalleled genomic resources and superior research support services
• Close interaction with our award-winning faculty members
• Partnerships with leading universities and medical centers
• Numerous courses and conferences focused on genetics, genomics and biomedicine
• Exceptional benefits, ample time off and other valuable programs
• Working for an institution that has repeatedly been voted among the top 15 “Best Places to work in Academia” in the world by readers of The Scientist
QUALIFICATIONS
• PhD (or nearing completion of PhD degree)
• Background in human genetics or genomics and disease research
• Publications (1st author highly advantageous)
For computational postdocs desired attributes include:
• Strong problem-solving skills, creative thinking, and enthusiastic about science
• Excellent communication skills and fully fluent spoken and written English
• Familiarity with next generation sequencing data sets and pre-processing
• Excellent programming skills,
• Familiarity with network building, mining, alignment algorithms
• Familiarity with bioinformatics resources, i.e., UCSC genome browser, NCBI.
For experimental postdocs desired attributes include:
• Strong problem-solving skills, creative thinking, and enthusiastic about science
• Excellent communication skills and fully fluent spoken and written English
• Familiarity with next generation sequencing data sets and data generation
• PhD in a genomics/genetics/biology or another relevant field
• Expertise in cellular and molecular biology techniques
About JAX:
The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,400 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center in Augusta, Maine, a genomic medicine institute in Farmington, Connecticut, and facilities in Ellsworth, Maine, Sacramento, California, and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!
EEO Statement:
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
4. Postdoctoral Associate | Bioengineering (Organ on a Chip) | Jalili Lab
Location: Farmington, Connecticut
Job Number: 7126125 (Ref #: JR003106)
Posting Date: Feb 21, 2023
Application Deadline: Open Until Filled
Job Description
Postdoctoral Fellow | Bioengineering (Organ on a Chip)
Jalili Lab
Farmington, CT
The Jalili lab will open in July 2023 and is seeking a highly motivated and talented postdoctoral fellow to join our team. The successful candidate will have the opportunity to work on cutting-edge research projects related to establishing an in vitro host immune-microbiome culture model for disease modeling, and vaccine and therapeutic development. We implement multiple technologies, like organoid engineering, organ on a chip platforms, microfluidics and microbiology for modeling skin and intestine inflammatory, autoimmune and cancer conditions, such as dermatitis, psoriasis, inflammatory bowel disease (IBD), Crohn’s disease (CD), ulcerative colitis (UC), and colon cancer. We will have access to both animal- and patient-derived cells/organoids and microbiome and we will use our complex Organ Chip models to study the underlying mechanisms of these diseases and the role of immune cells in regulating the dysbiosis in skin and intestinal microbial composition. The postdoctoral scientist will lead an exciting project that applies a broad range of cutting-edge technologies, such as microfabrication, Organ on Chip development, bioprinting, organoid culture, microbiome sequencing, single-cell transcriptomics, metagenomics and proteomics. This position will also explore and leverage collaboration with bioengineers and clinicians in the Jackson Laboratory, University of Connecticut, UConn Health and beyond. The ideal candidate would have a strong background in biomedical engineering, biomaterials science, microfluidics, bioprinting, immune engineering, and microbiology.
JAX has a vibrant and interactive research and training environment characterized by multidisciplinary scientific collaboration, unparalleled mouse resources, and outstanding core services. In addition to lab-based training, JAX has developed a unique program for trainees to expand their professional skills in science communication, entrepreneurship, teaching, mentoring and laboratory management to best prepare postdocs for future career opportunities. In Connecticut, JAX resides in the scenic town of Farmington, in the state’s capitol region. The Hartford region, which offers some of the best public schools in the country, is made up of both bigger cities and smaller, charming historic New England towns. JAX Genomic Medicine is also geographically located within 1.5-2 hours of Boston and New York and is close to multiple transportation systems, including bus lines, highways, railroads and international airports.
QualificationsPh.D. in biomedical sciences, biomedical engineering, microbiology, immunology or related field of study.
Strong skillsets in cell and tissue engineering
Strong training background in biomedical engineering, biomaterials, immunoengineering and cell biology.
Experience in microfabrication, 3Dprinting/bioprinting, biomaterials fabrication, in vivo models, bacterial cultures, host-microbiome interactions, and multi-omics approaches are particularly preferred.
Candidates should have at least one 1st author publication record in peer-reviewed journal.
Excellent writing and communication skills, able to work independently and effectively with other members in a productive team.
To apply
Interested candidates should apply with:A cover letter summarizing research training and accomplishments
A personal statement of scientific interests and career goals (1-page maximum)
Current CV with publications and contact information of three references
The Jalili lab supports postdocs that have either academic or non-academic long-term career goals, international candidates, women and candidates from all backgrounds. We truly believe in equal opportunity for all. For more information about the Jalili laboratory, please visit: https://www.jalili-lab.com.
About JAX:
The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,400 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center in Augusta, Maine, a genomic medicine institute in Farmington, Connecticut, and facilities in Ellsworth, Maine, Sacramento, California, and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!
EEO Statement:
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
5. Postdoctoral Associate | Bioengineering (Immune Monitoring and Engineering) | Jalili Lab
Location: Farmington, Connecticut
Job Number: 7126124 (Ref #: JR003105)
Posting Date: Feb 21, 2023
Application Deadline: Open Until Filled
Job Description
Postdoctoral Fellow | Bioengineering (Immune Monitoring and Engineering)
Jalili Lab
Farmington, CT
The Jalili lab will open in July 2023 and is seeking a highly motivated and talented postdoctoral fellow to join our team. The successful candidate will have the opportunity to work on cutting-edge research projects related to studying the host immune-microbiome interface in the context of autoimmune skin diseases, infectious diseases, and aging, using state-of-the-art engineering tools. We implement different engineering technologies, particularly microneedle skin patches, to longitudinally monitor the cross-regulation of skin microbiome and immune system in the context of the inflammatory and autoimmune skin conditions. The postdoctoral scientist will lead an exciting project that applies a broad range of cutting-edge technologies, such as microfabrication, microneedle patches, single-cell transcriptomics, metagenomics and proteomics in both mouse models and human patients. This position will also explore and leverage collaboration with bioengineers, dermatologists, microbiologist and immunologist in the Jackson Laboratory, University of Connecticut, UConn Health, University of Massachusetts Medical School and beyond. The ideal candidate would have a strong background in biomedical engineering, biomaterials science, immune engineering, immunology and microbiology.
JAX has a vibrant and interactive research and training environment characterized by multidisciplinary scientific collaboration, unparalleled mouse resources, and outstanding core services. In addition to lab-based training, JAX has developed a unique program for trainees to expand their professional skills in science communication, entrepreneurship, teaching, mentoring and laboratory management to best prepare postdocs for future career opportunities. In Connecticut, JAX resides in the scenic town of Farmington, in the state’s capitol region. The Hartford region, which offers some of the best public schools in the country, is made up of both bigger cities and smaller, charming historic New England towns. JAX Genomic Medicine is also geographically located within 1.5-2 hours of Boston and New York and is close to multiple transportation systems, including bus lines, highways, railroads and international airports.
QualificationsPh.D. in biomedical sciences, biomedical engineering, microbiology, immunology or related field of study.
Strong training background in biomedical engineering, biomaterials, immunoengineering and cell biology.
Experience in microfabrication, microneedles, biomaterials fabrication, in vivo models, immunophenotyping and bacterial cultures are particularly preferred.
Candidates should have at least one 1st author publication record in peer-reviewed journal.
Excellent writing and communication skills, able to work independently and effectively with other members in a productive team.
To apply
Interested candidates should apply with:A cover letter summarizing research training and accomplishments
A personal statement of scientific interests and career goals (1-page maximum)
Current CV with publications and contact information of three references
The Jalili lab supports postdocs that have either academic or non-academic long-term career goals, international candidates, women and candidates from all backgrounds. We truly believe in equal opportunity for all. For more information about the Jalili laboratory, please visit: https://www.jalili-lab.com.
About JAX:
The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,400 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center in Augusta, Maine, a genomic medicine institute in Farmington, Connecticut, and facilities in Ellsworth, Maine, Sacramento, California, and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!
EEO Statement:
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
6. Postdoctoral Associate | Varn Lab
Location: Farmington, Connecticut
Job Number: 7127513 (Ref #: JR003185)
Posting Date: Mar 7, 2023
Application Deadline: Open Until Filled
Job Description
Postdoctoral Associate
Varn Lab
Farmington, CT
The Varn Lab at The Jackson Laboratory for Genomic Medicine is seeking an experienced and highly motivated individual to oversee the wet lab operations of a research program investigating how tumor-microenvironment interactions shape the evolutionary trajectory of diffuse glioma, the most common malignant brain tumor in adults. The Varn Lab integrates genomic and molecular pathology approaches to study how the neurons, glial cells, and immune cells of the brain tumor microenvironment influence the transcriptional output of malignant glioma cells. As part of this work, we are seeking applicants that come from an experimental biology background and are looking to integrate cutting-edge genomic and microscopy techniques to investigate the role of the microenvironment in cancer evolution. For additional information, visit the Varn Lab’s webpage at jax.org.
The ideal candidate for this role will be motivated, curious, and have an established track record in experimental biology. Candidates will be expected to manage wet lab operations with minimal supervision and collaborate with other labs at The Jackson Laboratory to bring new techniques into the laboratory. Priority will be given to candidates with a training background in cell and molecular biology and immunofluorescence microscopy. Prior experience using in vitro cell line models of disease is essential. Individuals in this position will have access to state-of-the-art resources at The Jackson Laboratory and opportunities will exist to receive on-the-job training in computational analysis of genomic and spatial datasets. Overall, individuals will be well-supported to conduct exciting research that blends the fields of cell biology, microscopy, and computational biology.
Key Responsibilities After training, execute high-dimensional multiplex immunofluorescence experiments including developing antibody panels and microscopically imaging tissue samples
Maintain in vitro cell culture models of human cancer
Handle, organize, and process human tissue samples
Implement and maintain good biosafety practices
Collaborate with other labs at JAX to learn techniques and optimize protocols
Mentor and supervise trainees in wet lab techniques
Assist in writing manuscripts, reports, and funding proposals
Present results at lab meetings and institutional symposia
Qualifications PhD in Cell Biology, Molecular Biology, Genetics, or related field
Experience using common wet lab and microscopy techniques and maintaining in vitro cell culture models
Strong managerial, organizational, and communication skills that will allow for the execution of multiple projects with minimal supervision
Ability to drive projects forward and take initiative in solving problems
An established understanding and history of using good biosafety practices
A personal growth mindset and receptiveness to constructive feedback
A desire to work with others both collaboratively and as a mentor
Excellent written and oral communication skills to disseminate results and methods to the group
About JAX:
The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,400 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center in Augusta, Maine, a genomic medicine institute in Farmington, Connecticut, and facilities in Ellsworth, Maine, Sacramento, California, and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!
EEO Statement:
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
7. Postdoctoral Fellow | Mitochondria-Immune Crosstalk in Cancer | West Lab
Location: Bar Harbor, Maine
Job Number: 7136584 (Ref #: JR003307)
Posting Date: Mar 27, 2023
Application Deadline: Open Until Filled
Job Description
Postdoctoral Fellow | Mitochondria-Immune Crosstalk in Cancer
West Lab
Bar Harbor, ME
The West lab is relocating to The Jackson Laboratory and is seeking an independent, highly motivated postdoctoral fellow to lead a collaborative research program to investigate how mitochondrial genome instability shapes immune responses in the melanoma tumor microenvironment. The overall goals of our laboratory are to delineate how mitochondria function as central regulators of innate immune and inflammatory responses and to investigate how mitochondria-immune crosstalk contributes to disease and aging. Our laboratory pursues a multidisciplinary approach by integrating cell biology, immunology, and physiology using cutting-edge techniques including engineered mouse models, single-cell multi-omics, super-resolution imaging, and CRISPR-based cellular tools (www.westlaboratory.com).
The ideal candidate should have PhD in immunology or another relevant life-science discipline and have prior training in cell and molecular biology and/or immunology, wet lab and computational experience, and prior expertise using in vivo mouse models. The successful candidate will have access to JAX’s unique postdoctoral training program, which offers exceptional opportunities for professional development through mentoring, extensive support for grant/fellowship writing, and access numerous workshops and courses. Exceptional candidates can show early independence through the JAX Scholars Program. JAX has a vibrant and interactive research community with unparalleled resources and state of the art facilities for mouse phenotyping and behavioral studies, computational science, mass spectrometry, imaging science, and genome technologies. The JAX Cancer Center (JAXCC) is a National Cancer Institute-designated Cancer Center complemented by institutional education, resource, and service initiatives that support cancer research worldwide.
QUALIFICATIONSPhD in immunology, cell biology, molecular biology, or related field of study.
Strong training background in molecular biology, cell biology, and in vivo mouse models.
Experience in cell culture, flow cytometry, and single-cell technologies are particularly preferred.
Candidates should have at least one 1st author publication record in peer-reviewed journal.
Excellent writing and communication skills, able to work independently and effectively with other members in a productive team.
**Please submit your current CV, 3 letters of reference, and 1-page (maximum) statement of Research Interests and Career Goals at time of application. **
About JAX:
The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,400 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center in Augusta, Maine, a genomic medicine institute in Farmington, Connecticut, and facilities in Ellsworth, Maine, Sacramento, California, and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!
EEO Statement:
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
8. Postdoctoral Associate | Manipulating exercise-responsive circuits for neuroprotection | Bloss Lab
Location: Bar Harbor, Maine
Job Number: 7139068 (Ref #: JR003373)
Posting Date: Apr 10, 2023
Application Deadline: Open Until Filled
Job Description
Postdoctoral Associate – Manipulating exercise-responsive circuits for neuroprotection.
Bloss Lab
Bar Harbor, ME
A postdoctoral associate position is available in the laboratory of Dr. Erik Bloss at The Jackson Laboratory in Bar Harbor, Maine, to perform basic research investigating the mechanisms by which exercise-responsive circuits may be manipulated to prevent structural and functional decline of cortical synapses during aging and in mouse models of Alzheimer’s disease. This work will include chemogenetic and optogenetic manipulations of neural activity in aging mice performing exercise and multiple cognitive assays as well as high resolution microscopic reconstruction of synapses on hypothalamic and cortical neurons. The Bloss Lab offers a highly collaborative environment including opportunities with other leading laboratories in this field, nationally and internationally. For more information, please visit the Bloss lab website.
Responsibilities
The successful candidate will be able to plan, develop, execute, and analyze an independent research project.
Qualifications
M.D. or Ph.D. in biological or related sciences is required.
Strong training background in neuroscience is preferred.
Other areas of experience/training that would be valuable include cell biology, aging, exercise physiology, or cognitive/behavioral neuroscience.
Exceptional verbal and written communication skills;
Self-motivated and career-oriented individual preferred;
Minimum of one 1st author paper from graduate work.
To apply, a complete application must include a cover letter describing past research accomplishments, research interests, and career aspirations; a current CV; and the names of three references. Send to erik.bloss@jax.org.
About JAX:
The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visit www.jax.org
EEO Statement:
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
9. Postdoctoral Associate | Kidney Disease | Korstanje Lab
Location: Bar Harbor, Maine
Job Number: 7140691 (Ref #: JR003404)
Posting Date: Apr 18, 2023
Application Deadline: Open Until Filled
Job Description
Postdoctoral Fellowship in the Korstanje lab
The Korstanje lab studies the genetics underlying several forms of kidney disease, in particular modifier genes that affect the progression of Alport Syndrome, Polycystic Kidney Disease, and Diabetic Kidney Disease. The lab is seeking a postdoc to study the role of several proteins and microRNAs, both in cell culture and in mouse models, that have recently been associated with the progression of Diabetic Kidney Disease.
Responsibilities: Motivation and curiosity, and the desire to see things through are paramount.
Ability to work independently and in a team environment benefitting individual projects while supporting the overall goals of the lab.
Demonstrates the ability to plan, execute and analyze an independent research project.
The successful candidate will lead the studies in the lab with the help of lab- and animal- technicians.
Qualifications: Ph.D. in Biological Sciences.
Experience in cell culture and working with mice.
To apply, please submit (1) a cover letter describing past research accomplishments, research interest, and career goals, (2) a current CV; and (3) the contact information of three references.
About JAX:
The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visit www.jax.org.
EEO Statement:
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.
![Immunology Serology & A LABORATORY PERSPECTIVE By Christine_Dorresteyn_Stevens]](https://4.bp.blogspot.com/-O3EpVMWcoKw/WxY6-6I4--I/AAAAAAAAB2s/KzC0FqUQtkMdw7VzT6oOR_8vbZO6EJc-ACK4BGAYYCw/w100/nth.png)
![Immunology Serology & A LABORATORY PERSPECTIVE By Christine_Dorresteyn_Stevens]](https://4.bp.blogspot.com/-O3EpVMWcoKw/WxY6-6I4--I/AAAAAAAAB2s/KzC0FqUQtkMdw7VzT6oOR_8vbZO6EJc-ACK4BGAYYCw/w680/nth.png)
0 Comments
Feedback will be Appreciated