1) Postdoc Position on the Regulation of Plasmodesmata
Institute of Plant Molecular Biology
Plant Molecular Signaling
Employment contract
Researcher
Fixed-term
40
Full-time
1. 1. 2023
31. 12. 2022
Job description:
We are a research campus with a strong tradition in biosciences focused on complex ecological, evolutionary & developmental aspects of LIFE. We are looking for excellent & highly motivated candidates for a Post doctoral position on the regulation of plasmodesmata.
A postdoctoral researcher position is available in the newly established (since December 2020) laboratory of Dr. Michael Wrzaczek at the Institute of Plant Molecular Biology, Czech Academy of Sciences, Ceske Budejovice (https://www.umbr.cas.cz/en/departments/plant-molecular-signalling/). The group works on receptor-like protein kinases (RLKs), specifically on the cysteine-rich RLKs (CRKs), primarily in the model system Arabidopsis thaliana. The position aims at understanding the molecular roles of cysteine-rich receptor-like protein kinases in the regulation of plasmodesmata during the response to environmental stimuli and on elucidating the mechanisms of RLK recruitment to plasmodesmata. Some previous work can be found here: Kimura et al. Plant Cell 2020; Hunter et al., 2019 Plant Physiology; Vaattovaara et al., 2019 Communications Biology.
The project will be carried out in collaboration with working groups in France, Germany, and Czech Republic so a suitable candidate is expected to be willing to travel.
The researcher will use a diverse set of methods including cloning, recombinant protein expression and purification, generation and work with mutant and transgenic plants (analysis of protein complexes, confocal microscopy) as well as plant physiological assays for immunity, abiotic stress tolerance and development.
Requirements:
PhD
Molecular Biology, Biochemistry or a related field
Benefits:
We offer you:
Other employment benefits:
Additional information:
Česke Budějovice (2 hours away from Prague) is a city with over 750 years of tradition. It has history wherever you turn, excellent beer, breathtaking countryside around, and a growing international expert community at the Biology Centre CAS (BC CAS) and the University of South Bohemia (USB). Check out our Guide for Expats (https://www.bc.cas.cz/en/employees/) to read about life in the city and the Czech Republic.
The Biology Centre of the Czech Academy of Sciences holds the HR Excellence in Research Award. Our selection process is transparent, open, non-discriminating, and fair. For more information about the researchers' recruitment policy at our institution, see OTM-R (https://www.bc.cas.cz/en/employees/candidates/otm-r/).
Interviews and admission exams with selected applicants will be held in January 2023. The expected start date is as early as possible but is negotiable.
How to apply:
Please submit your structured CV including list of publications, motivation letter and a contact information for two academic referees via the APPLY button below by December 31th 2022. Please note that documents should be submitted in a single pdf file.
Informal inquiries can be directed via email to michael.wrzaczek@umbr.cas.cz.
2) Postdoc in Molecular Biology of Ticks
Institute of Parasitology
Biology of Disease Vectors
Laboratory of Molecular Biology of Ticks
Employment contract
Researcher
Fixed-term
40
Full-time
CZK 45 000 - 50 000
1. 3. 2023
31. 1. 2023
Job description:
A postdoctoral fellow position for two years (with an option of two-year extension) is immediately available in the laboratory of Dr Jan Perner at the Institute of Parasitology (IP, www.paru.cas.cz/en/) of the Biology Centre of the Czech Academy of Sciences (CAS, www.bc.cas.cz/en/) in Ceske Budejovice (Czechia).
The lab (www.researchgate.net/lab/Molecular-Biology-of-Ticks-Jan-Perner) employs genomic tools, reverse genetics, and biochemical approaches to understand the molecular basis of the tick-host interaction. The overarching goal of our scientific work has been to define key molecular interactions at both tick-host interfaces: (1) in tick midgut (nutrient sensing) and (2) at tick feeding site (immune and haemostatic modulation).
The specific tasks for the applicant will be tailor-made based on the existing experience or planned research direction.
Requirements:
PhD
Molecular Biology / Biochemistry / Immunology
Qualified candidates should have:
Strong applicant(s) will have knowledge or skills in one or more of the following areas:
Benefits:
Employment benefits:
In addition to that, we offer you:
Additional information:
Starting date is negotiable (during March 2023).
Ceske Budejovice (2 hours away from Prague) is a city with over 750 years of tradition. It has history wherever you turn, excellent beer, breathtaking countryside around, and a growing international expert community at the Biology Centre CAS (BC CAS) and the University of South Bohemia (USB). Check out our Guide for Expats (https://www.bc.cas.cz/en/employees/) to read about life in the city and the Czech Republic.
The Biology Centre of the Czech Academy of Sciences holds the HR Excellence in Research Award. Our selection process is transparent, open, non-discriminating, and fair. For more information about the researchers' recruitment policy at our institution, see OTM-R (https://www.bc.cas.cz/en/employees/candidates/otm-r/).
How to apply:
If interested, please send us your application by 31 January 2023 via the REPLY button below.
Applications will begin to be reviewed immediately and will continue to be reviewed until the position is filled.
If you have any queries, contact Dr Jan Perner (perner@paru.cas.cz).
- Date Posted:
- Deadline:4 January 2023
- Location:Czechia
Job description
The research group headed by Dr. Karel Souček conducting a basic and translational research in the field of cancer biology invites scientists to apply for a postdoctoral position. We wish to understand the plasticity of cancer cells in the context of tumor heterogeneity and progression. We consistently strive to publish our findings in reputable scientific journals, develop new methods and collaborate with clinicians to be able to translate our research results to practice. The key components of our daily activities include collaboration between experimentalists, medicinal chemists and clinicians, solidarity among the laboratory team and mentoring of young colleagues.
PROJECT ANNOTATION:
Haspin is an atypical Ser/Thr kinase with a well-described function in normal mitosis, but a largely understudied role in regulating cell cycle interphase, plasticity and cell fate decisions. The project will focus on elucidating differences in the Haspin interactome in interphase and mitosis and its role in cell cycle regulation, plasticity and fate. The research will combine several state-of-the-art methodologies (advanced proteomics, unique chemical probes) into unbiased and hypothesis-driven experimental strategies with the ambition to address important gaps in our understanding of Haspin function, molecular mechanism and regulation in fundamental biological processes. The goal is to advance our understanding of the precise role of this kinase in multiple aspects and contexts and to address its attractiveness as a therapeutic target.
SUCCESSFUL CANDIDATE SHOULD:
- be self-motivated, independent, team-oriented
- have received a PhD or its equivalent within the last 7 years.
- have a publishing record – in the last three years at least two publication outputs. The applicant must be the principal author of at least one publication.
- have experience in field molecular and cell/cancer biology, biochemistry, or biophysics
- have experience with research in (cancer) cell cycle and mitosis (an advantage).
- have excellent communication skills and the ability to collaborate with multiple teams.
APPLICATIONS:
- a CV (max. two A4 pages) including a summary of work experience, publication activity, involvement in research grants, etc.
- a cover letter describing motivation and previous experience
- contact information to at least three referees
- send applications to Karel Souček at ksoucek@ibp.cz
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