Post doctoral position at The university of British Columbia

1. POSTDOCTORAL RESEARCH FELLOW - ENZYME ENGINEERING AND DISCOVERY

POSTING EXPIRY

30 April 2022 - 12:00pm

Please refer to reference number PDFO-55859 when applying for this position.

Description

The Tokuriki Lab at the Michael Smith Laboratories, University of British Columbia (https://tokurikilab.msl.ubc.ca/) is looking for a postdoctoral researcher for enzyme engineering and discovery.

The research project will aim at developing a novel enzyme engineering and discovery platform combining a massive gene synthesis and high-throughput protein screening technologies. It will involve developing novel high throughput screening system using microfluidics-based emulsion droplet technology. Also the project combines microfluidics based high-throughput screening technology with deep sequencing approach to characterizing a large number of synthesized genes in the laboratory. Postdoctoral fellow candidates must possess a doctoral degree in biochemistry, bioengineering or a related discipline. 

Compensation is commensurate with experience and aligned with UBC postdoctoral salaries. The ideal candidate will either have wet-lab experience in molecular cloning, enzyme screening and assay, enzyme engineering and design, directed evolution and/or microfluidics engineering. 

Interested candidates should reach out to Dr. Tokuriki directly with CV and one page research interest: (tokuriki@msl.ubc.ca).

How to Apply?

Please send applications to tokuriki@msl.ubc.ca and refer to reference number PDFO-55859.

Desired start date: 01 May 2022

Duration: Fixed term / Temporary

Contract Type: Full Time

For More Detail please visit the official site and apply by Direct email to tokuriki@msl.ubc.ca

2. POSTDOCTORAL RESEARCH FELLOW IN EXERCISE, NUTRITION AND METABOLISM

Posting EXPIRY

1 July 2022 - 12:00pm

Please refer to reference number PDFO-55811 when applying for this position.

 

Description

The School of Kinesiology in the Faculty of Education at the University of British Columbia in Vancouver, Canada, invites applications for a Postdoctoral Fellow in Exercise, Nutrition and Metabolism. The successful Postdoctoral Fellow (PDF) candidate will join a dynamic and multidisciplinary team under the supervision of Dr. David Wright. The Wright Lab examines the effects of exercise, nutrition and pharmaceutical approaches on adipose tissue and liver metabolism, the underlying mechanisms therein and how alterations in these tissues impact whole body glucose and lipid homeostasis. Dr. Wright’s research group has lab space at both the Point Grey campus and BC Children’s Hospital Research Institute (https://bcchr.ca). The successful candidate will be expected to work on a CIHR funded project examining the role of GDF15 in fuel utilization and will be given the opportunity to develop their own, independent research questions.

Candidate: The ideal applicant will have a PhD in physiology, metabolism, biochemistry or a related field. Experience using preclinical animal models and basic biochemical/cellular approaches would be an asset, but is not required. The candidate must be able to work well in a team and be willing to take on a leadership role.

Opportunity: The University of British Columbia is located in Vancouver, British Columbia Canada which is world-renowned for its scenery and quality of living. UBC is world class research institute and the successful candidate will have the opportunity to collaborate with internationally recognized leaders in the School of Kinesiology (https://kin.educ.ubc.ca) and BC Children’s Hospital Research Institute (https://bcchr.ca).   Opportunities for international collaboration are also possible.

Application Process: Interested applicants should submit a CV and cover letter that details their experience and contact details for 3 references. Applications should be submitted to dcwrig01@mail.ubc.ca with ‘PDF Application’ in the email subject line. Applicants for the position will be evaluated in the order they are received.  This posting will remain open until the position is filled. The proposed start date for this position is August 2022 and is negotiable. The appointment will initially be for two years (renewed annually) and is extendable depending on funding availability. Applicants are encouraged to apply for competitive fellowship awards. Salary will be commensurate with qualifications, experience and awards secured.

How to Apply?

Please send applications to dcwrig01@mail.ubc.ca and refer to reference number PDFO-55811.

Desired start date: 01 Aug 2022

Duration: Fixed term / Temporary

Contract Type: Full Time

Also visit the official site and apply through email to  dcwrig01@mail.ubc.ca

3.   POSTDOCTORAL FELLOW: SINGLE-MOLECULE MICROSCOPY OF RNA-BASED MEDICINES AND VACCINES

POSTING EXPIRY

30 April 2022 - 12:00pm

Please refer to reference number PDFO-55536 when applying for this position.

 

Description

The Michael Smith Laboratories at the University of British Columbia in Vancouver, Canada, invites applications for a Postdoctoral Fellow (PDF) to join a dynamic team under the supervision of Dr. Sabrina Leslie. The successful candidate will work on a project that applies new biophysical tools to the development of genetic medicines and vaccines. The position is based in a cutting-edge academic research lab and the project will be driven by real and immediate needs, in collaboration with interdisciplinary scientists in the Nanomedicine Center of Excellence (NMIN).

About the high-throughput single-molecule CLiC imaging technology

The Leslie Lab’s single-molecule technology, Convex Lens-induced Confinement (CLiC), works by squeezing molecules into arrays of nanometer- to micrometer-scale “traps” that are large enough to allow the molecules to move and interact freely, but small enough to keep them confined so they can be imaged over extended periods with a high-powered optical microscope. The result is the world’s first tether-free and high-throughput single-molecule technology for analyzing individual molecular interactions in cell-like conditions. CLiC is capable of detecting, following, and understanding rare molecular events – like the drug/target interactions which can ‘silence’ genes associated with the onset of diseases – and by enabling direct visualization of how the drugs work, help us better engineer them.

About the position

The PDF will join a talented, energetic, interdisciplinary team of scientists and engineers working in a newly built laboratory. Our team collaborates with the spin-off company ScopeSys to respond to partnerships with leading drug and vaccine development research groups and companies. The emphasis of this position will be on applications of our single-molecule and single-cell imaging technology to improve and accelerate development of lipid-nanoparticle and RNA-based medicines and vaccines.

This project will require an interdisciplinary skill set, combining physical, chemical and biological expertise. The ideal candidate will possess experience and interest in some of the following areas:

§  Microscopy of molecules, nanomaterials, cells

§  Instrumentation, optics, engineering

§  Micro/nano-fabrication and lithography

§  Surface science and chemistry

§  DNA, RNA, lipid nanoparticles, cells

§  Biophysical assay and protocol development

§  Electronics, mechanical engineering, machining

The successful candidate will have a PhD and a demonstrated track record in research with first authored peer-review publications. The position will be filled by a well-organized, enthusiastic team player with strong communication skills, who enjoys hands-on lab work and creative trouble-shooting, and who is excited to try new things. Applicants should have a strong interest in building a career in biotechnology and/or nanotechnology research and development, pioneering new biophysical techniques, and commercializing cutting edge science and technology.

Application process

Interested applicants should submit a letter of application that highlights their experience, detailed curriculum vitae including a list of publications, and contact details for 3 references. Application materials should be combined into a single PDF document and sent to contact. leslielab@ gmail.com. Please include “PDF in single-molecule biophysics and biotechnology” in the e-mail subject line. Incorrectly addressed applications will not be considered. Review of applications will begin immediately and continue until the position is filled. We will contact you only if invited for an interview.

How to Apply?

Please send applications to leslielab@msl.ubc.ca and refer to reference number PDFO-55536.

Desired start date: 01 May 2022

Duration: Fixed term / Temporary

Contract Type: Full Time

Also visit the official site and apply through email to  leslielab@msl.ubc.ca