University of Oslo: Postdoctoral Fellow position in Outcompeting Cancer

Job description

A 3-year postdoctoral fellow position is available in the Tumor-Host Biology group at the Institute for Cancer Research at the Division for Cancer Medicine, Institute for Clinical Medicine, University of Oslo, from October, 2023.

The organization and research focus

The Tumor-Host Biology research group of Tor Erik Rusten seeks a postdoctoral researcher to join our team to study the interaction of tumor cells with host during tumorigenesis.

We use Drosophila melanogaster to model cancer biology and unravel the mechanisms underlying tumor-host interactions including tumor-microenvironment interactions, systemic effects and nutrient requirements for tumor growth in vivo. Using genetics, we break the tumor-host interaction one gene at a time in order to find vulnerabilities for tumor growth and damage to the host during carcinogenesis. The group employs a broad and multidisciplinary approach of advanced Drosophila genetics, cell culture, proteomics, metabolomics, RNASeq, electron microscopy, confocal microscopy, and detailed cell biology studies.

To enable this work, we have developed a powerful and unique genetic system that allows QF-QUAS generation of tumors while leaving the GAL4 system available for manipulation of tumor or any other cell type, or organ during tumor development in the translucent larva or adult. Using this system, we have already performed several genetic screens that identify key components of tumor-host interactions that fosters tumor development or decay of host physiology during cancer development. The candidate will work on cellular mechanisms promoting tumor growth on expense of the tumor microenvironment and host tissues

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More about the position

As one of the six members of CanCell, Centre of Excellence, focusing on unraveling mechanisms of tumor growth situated at the Institute of Cancer Research with 350 employees, we enjoy a strong academic environment for Cancer Research.

The ideal candidate is self-motivated, methodical, and an active team player and possess excellent oral and written communication skills.

The main purpose of the fellowship is to qualify researchers for work in higher academic positions within their disciplines.

Qualification requirements

Applicants must hold a degree equivalent to a Norwegian doctoral degree in molecular biology, cell biology or similar directly relevant disciplines for the positions. Doctoral dissertation must be submitted for evaluation by the closing date for the advertisement. Appointment is dependent on the public defense of the doctoral thesis being approved

Extensive experience in Drosophila genetic analysis of cell biology

Experience in confocal microscopy and other microscopy techniques

Experience in molecular biology

Experience in image analysis using Fiji or analogous programs and basic statistical analysis using Graphpad, R or other programs

Strong background in cancer biology or developmental biology

A good command of English is required

Personal skills

Team player

Well-organized

Flexible

Positive attitude

We offer

A positive-minded, international research environment with a wide variety of methods, an ideal environment to develop your own line of research using cancer models

Salary NOK 575 400 - NOK 657 300 per annum depending on qualifications in position as Postdoctoral Research Fellow (position code 1352)

A professionally stimulating working environment

Attractive welfare benefits and a generous pension agreement, in addition to Oslo’s family-friendly environment with its rich opportunities for culture and outdoor activities

How to apply

The application must includeA concise application letter (1 page) explaining your background, research interest and expertise

CV (summarizing education, positions, pedagogical experience, administrative experience and other qualifying activity)

Copies of educational certificates (academic transcripts only)

A complete list of publications

Two letters of reference

List of reference persons: 2-3 references (name, relation to candidate, e-mail and phone number)

The application with attachments must be delivered in our electronic recruiting system. Foreign applicants are advised to attach an explanation of their University's grading system. Please note that all documents should be in English (or a Scandinavian language).

In assessing the applications, special emphasis will be placed on the documented, academic qualifications as well as the candidates motivation and personal suitability. Interviews with the best qualified candidates will be arranged.

It is expected that the successful candidate will be able to complete the project in the course of the period of employment

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Formal regulations

Please see the guidelines and regulations for appointments to Postdoctoral fellowships at the University of Oslo.

No one can be appointed for more than one Postdoctoral Fellow period at the University of Oslo.

According to the Norwegian Freedom of Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.

Inclusion and diversity are a strength. The University of Oslo has a personnel policy objective of achieving a balanced gender composition. Furthermore, we want employees with diverse professional expertise, life experience and perspectives.

If there are qualified applicants with disabilities, employment gaps or immigrant background, we will invite at least one applicant from each of these categories to an interview.

Contact information

Associate Professor Tor Erik Rusten, phone number: +47 92231055, e-mail: t.e.rusten@medisin.uio.no

Questions regarding the online application form can be adressed to Senior HR Adviser Thoril Kristiansen, e-mail: thoril.kristiansen@medisin.uio.no

About the University of Oslo

The University of Oslo is Norway’s oldest and highest ranked educational and research institution, with 28 000 students and 7000 employees. With its broad range of academic disciplines and internationally recognised research communities, UiO is an important contributor to society.

The Institute of Clinical Medicine (Klinmed) is one of three institutes under the Faculty. Klinmed is responsible for the Faculty's educational and research activities at Oslo University Hospital and Akershus University Hospital. With about 800 employees spread over approximately 425 man-labour years, Klinmed is the university's largest institute. Our activities follow the clinical activity at the hospitals and are spread across a number of geographical areas.

Apply for this job

Deadline

4th September 2023

Employer

University of Oslo

Municipality

Oslo

Scope

Fulltime

Duration

Fixed Term

Place of service

Boks 1072 Blindern, 0316 Oslo