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Probiotics lectin: A promising agent in Medical Science

The function of probiotic recognition factors in the control of human microbiocenoses was overviewed based on its own findings. Probiotic lectin systems (PLS) function like a member of the cytokine network of the body, imitating the primary properties of probiotics, synchronising metabolic processes.

They contribute to the direct and indirect partial inactivation of microbial virulent agents, degrade and lyse biofilms of opportunistic microbial clinical isolates as a significant factor affecting microbial solid phased and suspension biorhythms. PLS is involved in regulatory relationships between interacting microbiocenosis cell populations on the probiotic cell surface (as in "Yeast like fungi Probiotic" cases).


Probiotic  lectin  systems (PLS) affects parasitism's microbiocenosis (intermyco) status, Act as part of the limitation factors of mycochain guidance communications. The findings show that PLS has a high potential for medical biotechnology.



Ordered mucosal microbiocenoses (MMB) are large biofilms acting as communicative bodies (CB) that play an important role in the defence of human intestinal and urogenital tract diseases. On the one hand, the "Yeast-like fungi populations-Probiotic bacteria (PB)" systems are used by sensory systems to measure the current MMB status of a normal or disease. Candida species represent messenger, bridge and intercellular communications linking MMB and human mucosa as eukaryotic constants. 

the authors said "We indicated that as fungal and/or bacterial CB, MMB represents early changes that indicate possible disease onset. Structure-functional related conditionally pathogenic and symbiotic/probiotic compartments contain MMB". Supporting and establishing the conception of the role of MMB as relevant and important system for the constituents of the organism's superprotection framework. 


Additional findings and views are provided on the prophylactic and therapeutic potential of the MMB symbiotic/probiotic compartment. New microecological relationship data are identified between opportunistic/pathogenic fungal and probiotic/synbiotic MMB bacterial compartments. PL affects biorhythms of Candida species, restricts the action of mycoparasitism, contributes to drug and factor antifungal multisynergism, suppresses, limits and/or removes certain virulent factors of Candida. The "PB/PL-Candida species" method can be helpful for early assessment and further preventive correction of cervico-vaginal and other mucosal pathological status.

At the level of various planctonic and BF stages of fungal-bacterial massifs of MMB, PL (also PL-GC complexes), PB are effectively involved in anti-Candida action and Candida specie/ subspecies interniche combined redistribution.

They explained " Our Results demonstrate multisynbiotics' current potential and suggest opportunities for new ways to create antifungal compositions". In researching microecological relationships within any MMB, mucosal cavities or mucosal organs, the anti-fungal approaches and strategies suggested are universal.

PL are promising agents followed by BF lysis (agents achieving a large synergistic AMA as in cases of chronic BF-based diseases) to initiate BF degradation. One of the techniques is to use PL's organised combined impact as targets within a CB against metabolically active selected microbial target isolates within BF, including staphylococcal, yeast-like fungal or mixed associates. 

The goal of the results was to develop new medical biotechnology strategies against BF-based infections such as staphylococcosis and staphylococcal candidosis. New antibiotics and bacteriocin-like agents would be useful in the study of the proposed methodologies.

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